How Naltrexone Implants Work for Alcohol & Opioid Addiction

Opioid and alcohol use disorders are a growing concern in the United States, especially with the rise in overdose deaths. In 2021 alone, 107,622 drug-involved overdose deaths were reported in the country, and opioids accounted for 80,816. In the same year, there were over 52,000 alcohol-induced deaths in the US.

The increase in substance abuse and overdose cases indicates the need for addiction maintenance treatments. While traditional treatments for opioid and alcohol use disorder do a great job of helping people get off of drugs, they do little to prevent overdose cases. Once a recovering addict leaves the treatment facility, they may face triggers that can result in relapse and overdose.

That's why many medical institutes worldwide are still trying to find innovative ways to enhance the convenience and chances of long-term sobriety. Naltrexone implants are one such innovative treatment option. These implants provide long-term maintenance from alcohol and opioids by reducing the risk of cravings and relapse.

What are Naltrexone Implants?

Naltrexone implants are small pellets that contain the medication naltrexone. Naltrexone is an opioid antagonist medication that blocks the effects of opioids and alcohol on the brain, thus helping manage cravings.

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The principle behind this medication-assisted treatment is that if someone can't feel the desired effect of drugs, they won't be motivated to use them. Over time, the positive association with opioids or alcohol will fade, and temptations won't be present.

When the implant is inserted under the skin, it slowly releases Naltrexone into the body over several weeks to months. This extended release can help reduce cravings for opioids or alcohol and prevent relapse. In some cases, it can also help curb opioid overdose cases.

Naltrexone implants have shown promising results in treating alcohol and opioid addiction, mainly when used in conjunction with other forms of evidence-based treatment, like medication, counseling, and support groups. This holistic approach addresses substance use disorders and the mental health aspect.

How Naltrexone Implants Work for Alcohol and Opioid Addiction

Naltrexone is an opioid antagonist medication that works by blocking the opioid receptors in the brain. The implants provide a constant level of medication in the body, which can help to keep the opioid receptors blocked and reduce the risk of relapse.

Naltrexone implants have several advantages as they:

Are safe and effective when used as directed.
Are not addictive, meaning you can stop using them at any time without withdrawal effects.
Provide a sustained level of medication over several months. This can be particularly helpful when someone relapses, as they'll still have the implant protection.
Lower the chances of forgetting or purposefully avoiding taking prescriptions to drink alcohol or use opioids.
Readily binds to opioid receptors.
Provide ample time for the brain to rewire and heal from the damages caused by long-term alcohol or opioid use.

Weakness of Naltrexone Treatment

Despite the advantages of Naltrexone, there are some downsides as well. These include:

Need for detox – the treatment can only begin after alcohol or drugs have been cleared from the body. This may take about 7-10 days. Starting the treatment before detox may lead to intense and persistent withdrawal.
Potential side effects, which we'll discuss below.
Some sources cite the lack of consistency in the manufacturing of different implants available in the market. As such, some might break up rather than dissolve over time.

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How Are Naltrexone Implants Administered?

Naltrexone implants are small, sterile pellets implanted under the skin in a minor surgical procedure. The procedure is usually done in an outpatient setting, meaning you won't need to stay overnight in a hospital.

First, a healthcare professional will clean and numb the area where the implant will be inserted. This is done with a local anesthetic, so you'll be awake during the procedure but won't feel any pain.

Next, the healthcare professional will make a small incision in your lower abdomen skin. They'll then insert the naltrexone implant into the pocket they've created under the skin and close the incision using stitches or adhesive strips. They will also apply a sterile dressing to the area to protect it as it heals.

The procedure usually takes about 20 minutes or less you can go home the same day.

Side Effects of Naltrexone Implants

Naltrexone is generally safe. But like any medication, it can cause side effects. Here are some of the potential side effects of naltrexone implant:

Pain, swelling, or redness at the implant site
Infection at the implant site
Bleeding or bruising at the implant site
Itching or rash at the implant site
Nausea or vomiting, headache or dizziness
Diarrhea
Anxiety or nervousness
Fatigue or weakness
Liver problems
Allergic reactions

It's important to note that these side effects are usually mild and temporary, and most people tolerate the medication well. However, if you experience severe or persistent side effects, you should contact your healthcare provider immediately.

If you have any medical conditions or take other medications, inform your healthcare provider before starting a naltrexone implant to ensure it's safe and effective for you.

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Starting Naltrexone Treatment

Before starting Naltrexone, you must undergo an assessment to ensure you're suited for treatment. A good candidate for Naltrexone treatment would typically meet the following criteria:

Remain at risk of relapse without treatment
Have completed a detoxification program and have been opioid- or alcohol-free for at least 7-10 days
Used low doses of opioids or for a short time
Have a solid motivation to stop using opioids or alcohol
Are currently using other forms of evidence-based medications but would like to switch to Naltrexone
Have previously relapsed with other MAT treatments, like buprenorphine-naloxone or methadone

Naltrexone implants are a cutting-edge treatment for addiction to opioids, heroin, and alcohol. But the FDA has not approved the implantable version of Naltrexone for use in America. The treatment is only available in Europe and Australia. Still, many centers offer other forms of Naltrexone, which also offer long-term maintenance.

For more details about Naltrexone, reach out to More Than Rehab today.

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Do Drug Implants Like Naltrexone Really Work?

Drug and alcohol addiction has been around for centuries and it has increasingly become a major issue in the United States. At first, people who suffered from substance abuse problems were considered degenerates and were often blamed for not having enough self-control to get sober and stop abusing drugs or alcohol. Today, thanks to medical science and research, our understanding of substance abuse problems and drug addiction is much farther advanced. We have developed evidence based treatments for addiction such as drug implants, like Naltrexone and others that greatly increase the chances of a successful recovery.

The majority of respected health professionals agree that addiction is a disease that is often characterized by the inability to stop using drugs or alcohol despite having suffered negative consequences in the past. To those who do not know, there is more to addiction than originally meets the eye.

Addiction is a treatable disease

For decades, there are those who have understood that addiction is a disease. Eventually, this understanding is what led to the creation of 12-step programs such as Alcoholics Anonymous (AA) and Narcotics Anonymous (NA). As more and more people gained knowledge about the disease of addiction, other more intense forms of treatment such as inpatient drug and alcohol rehabilitation programs began to develop.

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While drug addiction and substance abuse problems have been around for quite some time now, there is a growing concern for the treatment of the current opioid epidemic in our country. For many diseases, there is no one-size fits all treatment, the same can be said with drug and alcohol addiction. What works for some, may not work for others. That is why they continue to develop new methods of treatment for this life-changing disease.

How drug implants like Naltrexone help people recover from addiction

It is estimated that nearly 128 people die each day from an opioid addiction and nearly 15 million adults suffer from alcoholism in the United States alone. For many, the chance to recover is slim. One example of how researchers and medical professionals are trying to provide more effective treatment for the addiction to opioid drugs such as morphine and heroin, as well as for the use of alcohol, are drug implants like the commonly used Naltrexone implant. Naltrexone is an opioid antagonist that blocks the effects of opioids and alcohol at the receptor level, which helps to prevent abuse, curb relapse, and sustain recovery from an opioid addiction and alcoholism.

Over time, repeated use of addictive substances will change the structure and function of the brain. Most drugs target an area of the brain known as the reward center, releasing chemical messengers known as neurotransmitters that illicit a feel-good response. This is to help ensure that desired actions, usually necessary for survival, get repeated again, such as eating good food or having sex. After each use, the brain adapts. Eventually, the brain needs more and more of the substance in order to feel the same effects. Not only will they begin to need more and more of the same drug, but the excess release of these chemical messengers will essentially trick the brain into believing that it needs this substance in order to survive. It will also associate people, places, or things with this action that it believes is necessary for survival, which can trigger cravings for the drug, even months or years after they have gotten sober. All of these reasons combined is why it is extremely difficult for some people to get and stay sober.

For opioid related drugs specifically, they target and bind to pain receptors, blocking any sensation someone might feel from pain. Opioid antagonists, as mentioned earlier, block the effects of opioids at the receptor level. The effects of alcohol are also blocked at the opioid receptor sites, helping to reduce the liking and craving of both substances. There are several other treatment methods that are predecessors to Naltrexone implants. Those are drugs such as oral Naltrexone, or methadone, both of which are effective for the treatment of opioid addiction and alcoholism. However, part of the problem with oral opioid antagonists is maintaining consistency among users who need to take it every day, or as prescribed.

In 1984, the Food and Drug Administration (FDA) approved drugs like Naltrexone for the treatment of opioid addiction and later in 1994 for alcoholism. While proven to be extremely effective, for patients who are recovering from opioid addiction or alcoholism, taking their daily medication, medication adherence or compliance, is a real struggle and can be a huge setback to recovery. To help solve this problem, scientists and medical professionals have begun using and developing drug implants. For instance, there are several widely regarded studies that show the effectiveness of Naltrexone implants and thousands of treatment facilities have begun utilizing it as a treatment method.

What are Naltrexone implants? How do they work?

Naltrexone implants are typically small medication pellets that get planted beneath the skin, slowly releasing medication usually lasting anywhere between 2-6 months. Thus, eliminating the need to take a daily medication. This has significantly increased the effectiveness of daily medication treatment methods for opioid addiction and

alcoholism. For instance, one study found that Naltrexone implants reduced the risk of opioid related death by nearly 50%. Additionally, when Naltrexone implant treatment is combined with other modes of treatment such as psychotherapy, it has been shown to be far more effective than just one mode of treatment alone.

The Naltrexone implant may be right for you if you have struggled with cravings, have had relapses in the past, or have had any difficulty with taking medication every day. Naltrexone has been proven to be an effective treatment for opioid addiction and alcoholism for many years, and the implant helps eliminate the need to take medication daily. This has saved many patients from having to remember to take their medication every day, or from having to find the time to get to the clinic every day in order to receive treatment.

If you or someone you know is struggling with an addiction to opioids or alcohol, let our family of staff at More Than Rehab help you get treatment today! We understand what it’s like to suffer from an addiction and we wish nothing more than to help show you the tools to lead a healthy and sober life! Please, reach out to us today.