The Efficacy of CBD in Treating Opioid Withdrawal Symptoms

CBD has gained a reputation as a magical elixir that can seemingly heal everything from stress and insomnia to cancer and chronic pain. People are captivated by the potential of CBD as a multipurpose remedy, and its purported benefits have fueled a surge in its popularity. However, most of these claims are not based on scientific evidence, and the only medical indication that CBD has been proven to treat humans is epilepsy.

That said, there has been a growing interest and scientific research on the potential efficacy of CBD in managing opioid withdrawal symptoms. In fact, a recent study suggests that CBD curbs cravings in people with opioid dependence. According to the study, the potential to reduce cue-induced craving and anxiety offers a strong basis for more research on the substance as a treatment option for opioid use disorder. 

This couldn't come at a better time, considering the pressing need to address the opioid crisis and provide effective interventions for those struggling with addiction. Opioid addiction has reached alarming levels, causing immense harm to individuals, families, and communities worldwide. In 2021, 80,816 people lost their lives due to opioids.

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However, the researchers in the study note that the study was very narrow and only used specific, standardized amounts of CBD. As such, the results don't suggest buying a jar or bottle of over-the-counter CBD will help with opioid cravings.

What is CBD?

CBD, or cannabidiol, is a naturally occurring compound in cannabis plants. It is one of the many cannabinoids present in the plant, alongside THC (tetrahydrocannabinol). Unlike THC, CBD is not psychoactive, meaning it does not induce a "high" sensation commonly associated with cannabis use. CBD is typically extracted from hemp plants to produce numerous products such as oils, tinctures, edibles, and topicals.

CBD has gained attention for its potential therapeutic use. It interacts with the body's endocannabinoid system, which regulates various physiological processes, such as pain sensation, mood, sleep, and immune function. CBD is believed to have anti-inflammatory, analgesic, anxiolytic (anti-anxiety), and neuroprotective properties.

While CBD has shown promise in treating certain medical conditions, such as epilepsy, its broader applications as an alternative treatment in areas like addiction recovery, pain management, sleep disorders, and anxiety are still being explored. More research is needed to fully understand its effects, optimal dosage, and potential interactions with other medications.

Addiction is a Brain Disease

Before we dive into why or how CBD might help in addiction recovery, it's important to look at how substance abuse alters normal behavior and brain function. Addiction is a complex brain disease characterized by compulsive drug-seeking behavior and the inability to control substance use despite negative consequences.

Addiction changes the way the brain processes information. It deregulates the brain's reward system (which is responsible for reinforcing pleasurable experiences), leading to a heightened sensitivity to drug-related cues and a diminished response to natural rewards. This happens with most substances, including nicotine, alcohol, cocaine, meth, and opioids.

When addiction develops, it becomes hard to stop. Attempts to quit might result in withdrawal symptoms that are uncomfortable and challenging to manage. Common opioid withdrawal symptoms include anxiety, nausea, rapid heartbeat, abdominal cramps, and intense cravings.

These symptoms can be debilitating and are often more intense for the first one to two weeks. Sometimes, they can linger for months and contribute to relapse or continued drug use.

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Potential Benefits and Effectiveness of CBD in Mitigating Withdrawal Symptoms

While the scientific evidence is still developing, preliminary studies suggest several ways CBD may play a role in alleviating withdrawal symptoms. One study found that CBD mitigated cravings among those with OUD who had already stopped opioid use. Researchers also found that the compound reduced:

Most of these symptoms occur during opioid withdrawal. In theory, this means that physicians could consider adding the compound to opioid withdrawal treatment plans to manage the symptoms. But more research is still needed to establish the direct effects of CBD on opioid withdrawal and the best formulations and dosages. Here's a closer look at how cannabinoids may help mitigate opioid withdrawal symptoms:

Craving Reduction

One of the key challenges during withdrawal is intense cravings for the substance of abuse. CBD can help mitigate this by reducing cue-induced cravings, especially among those who use heroin. Studies on rats noted a decrease in drug-seeking behavior when rats were taken off heroin and given CBD. A small human study also found similar effects lasting at least a week.

Anxiety and Stress Reduction

Withdrawal from opioids often triggers heightened anxiety and stress levels. CBD has been studied for its anxiolytic properties, with research indicating its potential to reduce anxiety symptoms. According to one review, CBD interacts with serotonin, type 1 receptor (CB1R), and other brain receptors that regulate anxiety-induced behaviors.

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Pain Relief

Opioid withdrawal is commonly associated with various physical symptoms, including muscle aches, joint pain, and general discomfort. CBD has shown analgesic properties and has been explored as a potential alternative to traditional pain medications. It may help alleviate withdrawal-related pain and discomfort. Clinical trials have also found CBD well-tolerated with no significant side effects, even when co-administered with a potent opioid agonist.

Sleep Improvement

Insomnia and disrupted sleep patterns are common during opioid withdrawal. CBD has been investigated for its potential to improve sleep quality and address sleep disorders. CBD may indirectly contribute to better sleep during withdrawal by promoting relaxation and reducing anxiety.

CBD has shown potential in withdrawal symptom management. It can help reduce anxiety, improve sleep, curb cravings, and in withdrawal relief. While more extensive research is needed to fully understand its effectiveness, the existing studies provide encouraging results. It is important to note that cannabinoid treatment should be part of a holistic care plan alongside counseling, behavioral therapies, and other evidence-based interventions.

It is also a good idea to take CBD while under medical supervision, especially when dealing with a serious issue like opioid use disorder or chronic pain. Healthcare professionals can coordinate your care and ensure CBD is used with other appropriate treatments for the best possible outcomes.

They will also offer expert guidance, monitor and adjust treatment and offer support and guidance. Most importantly, they will ensure that you have access to reputable CBD products that have undergone proper testing for purity and accurate labeling. Like other natural remedies, CBD is largely unregulated, and it can be hard to know which products have been formulated responsibly.

If you, or a loved one is experiencing a physical dependence on opioids, More Than Rehab is here to help. Contact us today. We are available 24/7, 365 days a year.

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How Naltrexone Implants Work for Alcohol & Opioid Addiction

Opioid and alcohol use disorders are a growing concern in the United States, especially with the rise in overdose deaths. In 2021 alone, 107,622 drug-involved overdose deaths were reported in the country, and opioids accounted for 80,816. In the same year, there were over 52,000 alcohol-induced deaths in the US. 

The increase in substance abuse and overdose cases indicates the need for addiction maintenance treatments. While traditional treatments for opioid and alcohol use disorder do a great job of helping people get off of drugs, they do little to prevent overdose cases. Once a recovering addict leaves the treatment facility, they may face triggers that can result in relapse and overdose. 

That's why many medical institutes worldwide are still trying to find innovative ways to enhance the convenience and chances of long-term sobriety. Naltrexone implants are one such innovative treatment option. These implants provide long-term maintenance from alcohol and opioids by reducing the risk of cravings and relapse.

What are Naltrexone Implants? 

Naltrexone implants are small pellets that contain the medication naltrexone. Naltrexone is an opioid antagonist medication that blocks the effects of opioids and alcohol on the brain, thus helping manage cravings. 

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The principle behind this medication-assisted treatment is that if someone can't feel the desired effect of drugs, they won't be motivated to use them. Over time, the positive association with opioids or alcohol will fade, and temptations won't be present.

When the implant is inserted under the skin, it slowly releases Naltrexone into the body over several weeks to months. This extended release can help reduce cravings for opioids or alcohol and prevent relapse. In some cases, it can also help curb opioid overdose cases.

Naltrexone implants have shown promising results in treating alcohol and opioid addiction, mainly when used in conjunction with other forms of evidence-based treatment, like medication, counseling, and support groups. This holistic approach addresses substance use disorders and the mental health aspect. 

How Naltrexone Implants Work for Alcohol and Opioid Addiction

Naltrexone is an opioid antagonist medication that works by blocking the opioid receptors in the brain. The implants provide a constant level of medication in the body, which can help to keep the opioid receptors blocked and reduce the risk of relapse.

Naltrexone implants have several advantages as they:

Weakness of Naltrexone Treatment

Despite the advantages of Naltrexone, there are some downsides as well. These include:

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How Are Naltrexone Implants Administered?

Naltrexone implants are small, sterile pellets implanted under the skin in a minor surgical procedure. The procedure is usually done in an outpatient setting, meaning you won't need to stay overnight in a hospital.

First, a healthcare professional will clean and numb the area where the implant will be inserted. This is done with a local anesthetic, so you'll be awake during the procedure but won't feel any pain.

Next, the healthcare professional will make a small incision in your lower abdomen skin. They'll then insert the naltrexone implant into the pocket they've created under the skin and close the incision using stitches or adhesive strips. They will also apply a sterile dressing to the area to protect it as it heals. 

The procedure usually takes about 20 minutes or less you can go home the same day. 

Side Effects of Naltrexone Implants

Naltrexone is generally safe. But like any medication, it can cause side effects. Here are some of the potential side effects of naltrexone implant:

  1. Pain, swelling, or redness at the implant site
  2. Infection at the implant site
  3. Bleeding or bruising at the implant site
  4. Itching or rash at the implant site
  5. Nausea or vomiting, headache or dizziness
  6. Diarrhea
  7. Anxiety or nervousness
  8. Fatigue or weakness
  9. Liver problems
  10. Allergic reactions

It's important to note that these side effects are usually mild and temporary, and most people tolerate the medication well. However, if you experience severe or persistent side effects, you should contact your healthcare provider immediately. 

If you have any medical conditions or take other medications, inform your healthcare provider before starting a naltrexone implant to ensure it's safe and effective for you.

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Starting Naltrexone Treatment

Before starting Naltrexone, you must undergo an assessment to ensure you're suited for treatment. A good candidate for Naltrexone treatment would typically meet the following criteria:

Naltrexone implants are a cutting-edge treatment for addiction to opioids, heroin, and alcohol. But the FDA has not approved the implantable version of Naltrexone for use in America. The treatment is only available in Europe and Australia. Still, many centers offer other forms of Naltrexone, which also offer long-term maintenance.

For more details about Naltrexone, reach out to More Than Rehab today.

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How Medication-Assisted Treatment Can Aid Addiction Recovery

Addiction to drugs or alcohol can cause long-term changes to the structure and functioning of the brain. These changes make it hard for someone to quit using despite the harm it causes. Even in addiction recovery, people can experience relapses due to cravings - it's why addiction is often referred to as a relapsing disease.

The reason is that repeated substance abuse causes the brain to build much stronger connections between the substance and associated cues or triggers. Cues can be feelings, things, places, or people that make them want to use substances again.

Understanding how these substances affect the brain and the body is critical to understanding how medication-assisted treatment (MAT) works. This article will discuss how MAT can help addiction recovery and relapse prevention. But first, let's ensure we're on the same page.

What is Medication-Assisted Treatment (MAT)?

Medication-assisted treatment (MAT) is a type of treatment that helps people struggling with addiction overcome their dependence. It combines FDA-approved medications, such as opioid antagonists and pain relievers, with counseling and behavioral therapies to provide short-term relief from cravings and long-term recovery support.

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By combining pharmacological interventions with evidence-based therapies, MAT offers a comprehensive approach to addiction recovery, offering people the best chance of successful long-term sobriety.

MAT is used to treat various substance use disorders, including alcohol use disorder and opioid addiction. It can also prevent or reduce opioid overdose. The medication normalizes brain chemistry, normalizes body functions, relieves physiological cravings, and blocks the euphoric effects of substances. And since everyone is different, the clinically driven program is customized to meet each patient's needs. 

How Does MAT Work?

MAT works by reducing cravings and providing a "safety net" that helps people recovering from addiction stay away from drugs or alcohol. It's important to understand that MAT medications are not a magic cure for addiction but rather a tool to help individuals recover.

MAT works by targeting the reward circuitry of the brain. The reward pathways make us feel good when we engage in certain behaviors, like eating sweet foods or taking drugs. MAT medications help reduce cravings by targeting the same brain pathways responsible for our drug-seeking behavior.

For instance, MAT medications like buprenorphine can reduce the reward we feel from taking opiates and make it easier to resist cravings. Other MAT medications, like naltrexone, can block the receptors in our brains that would usually be activated by opiates or alcohol. This helps reduce cravings and the euphoric effects of drug or alcohol use.

MAT medications can also help restore balance in our brain chemistry that has been altered by substance use. This can help reduce withdrawal symptoms and cravings, allowing people to focus on therapy, healthy lifestyle changes, and other components of their recovery program.

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How Effective Are MAT Medications in Addiction Recovery?

MAT medications can be a powerful tool in addiction recovery. When used as part of an integrated treatment plan, MAT has been found to:

While it's hard to pinpoint a single seminal paper in the field, there's a substantial body of evidence that speaks to the efficacy of MAT. For instance, one study found that opioid overdose deaths were reduced as buprenorphine became more popular in Baltimore. Another review paper found that Methadone can keep those dependent on heroin in treatment programs and reduce their use of heroin. 

Limitations of Medication as a Sole Approach 

MAT medication can help reduce cravings and withdrawal symptoms but cannot address the underlying issues that contribute to the addiction. Mental health, trauma, and lifestyle issues may have been a factor in the person's development of a habit, and these cannot be addressed through medication alone.

For this reason, MAT should be used as part of an integrated treatment plan that includes counseling, behavioral therapies, and ongoing support structures - like 12-step programs, sober living arrangements, etc. The word "assisted" in medication-assisted treatment emphasizes that medications are only one part of the overall treatment plan.

MAT Medication

The FDA has approved several medications for the treatment of addiction. The most common types are:

Opioid Use Disorders Medications

Methadone, Buprenorphine, and Naltrexone are used to treat opioid dependency. These MAT medications work for opioids like heroin and prescription painkillers.

Alcohol Use Disorders Medications

Acamprosate, Disulfiram, and Naltrexone are used to treat alcohol use disorders.

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Opioid Overdose Prevention Medication

Naloxone is used to treat opioid overdoses. It works by blocking the effects of opioids in the brain and reversing an overdose. Naloxone is available in a nasal spray and can be used by family members or friends to treat an overdose.

While prescribed medications can be a powerful tool in addiction recovery, they are only one piece of the puzzle. MAT should be combined with therapy, lifestyle changes, and other strategies to achieve maximum success in recovery. With the right approach, MAT can provide an effective and safe pathway to recovery.

Find MAT Treatment

If you or someone you love is struggling with addiction, exploring MAT medications as part of your treatment options may be helpful. Many substance use treatment centers offer MAT-based health services. At More Than Rehab, we offer MAT treatment as part of our primary care model. Our doctors, nurses, and counselors work together to provide personalized care and the best possible outcomes for each patient.

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