How Naltrexone Implants Work for Alcohol & Opioid Addiction

Opioid and alcohol use disorders are a growing concern in the United States, especially with the rise in overdose deaths. In 2021 alone, 107,622 drug-involved overdose deaths were reported in the country, and opioids accounted for 80,816. In the same year, there were over 52,000 alcohol-induced deaths in the US.

The increase in substance abuse and overdose cases indicates the need for addiction maintenance treatments. While traditional treatments for opioid and alcohol use disorder do a great job of helping people get off of drugs, they do little to prevent overdose cases. Once a recovering addict leaves the treatment facility, they may face triggers that can result in relapse and overdose.

That's why many medical institutes worldwide are still trying to find innovative ways to enhance the convenience and chances of long-term sobriety. Naltrexone implants are one such innovative treatment option. These implants provide long-term maintenance from alcohol and opioids by reducing the risk of cravings and relapse.

What are Naltrexone Implants?

Naltrexone implants are small pellets that contain the medication naltrexone. Naltrexone is an opioid antagonist medication that blocks the effects of opioids and alcohol on the brain, thus helping manage cravings.

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The principle behind this medication-assisted treatment is that if someone can't feel the desired effect of drugs, they won't be motivated to use them. Over time, the positive association with opioids or alcohol will fade, and temptations won't be present.

When the implant is inserted under the skin, it slowly releases Naltrexone into the body over several weeks to months. This extended release can help reduce cravings for opioids or alcohol and prevent relapse. In some cases, it can also help curb opioid overdose cases.

Naltrexone implants have shown promising results in treating alcohol and opioid addiction, mainly when used in conjunction with other forms of evidence-based treatment, like medication, counseling, and support groups. This holistic approach addresses substance use disorders and the mental health aspect.

How Naltrexone Implants Work for Alcohol and Opioid Addiction

Naltrexone is an opioid antagonist medication that works by blocking the opioid receptors in the brain. The implants provide a constant level of medication in the body, which can help to keep the opioid receptors blocked and reduce the risk of relapse.

Naltrexone implants have several advantages as they:

Are safe and effective when used as directed.
Are not addictive, meaning you can stop using them at any time without withdrawal effects.
Provide a sustained level of medication over several months. This can be particularly helpful when someone relapses, as they'll still have the implant protection.
Lower the chances of forgetting or purposefully avoiding taking prescriptions to drink alcohol or use opioids.
Readily binds to opioid receptors.
Provide ample time for the brain to rewire and heal from the damages caused by long-term alcohol or opioid use.

Weakness of Naltrexone Treatment

Despite the advantages of Naltrexone, there are some downsides as well. These include:

Need for detox – the treatment can only begin after alcohol or drugs have been cleared from the body. This may take about 7-10 days. Starting the treatment before detox may lead to intense and persistent withdrawal.
Potential side effects, which we'll discuss below.
Some sources cite the lack of consistency in the manufacturing of different implants available in the market. As such, some might break up rather than dissolve over time.

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How Are Naltrexone Implants Administered?

Naltrexone implants are small, sterile pellets implanted under the skin in a minor surgical procedure. The procedure is usually done in an outpatient setting, meaning you won't need to stay overnight in a hospital.

First, a healthcare professional will clean and numb the area where the implant will be inserted. This is done with a local anesthetic, so you'll be awake during the procedure but won't feel any pain.

Next, the healthcare professional will make a small incision in your lower abdomen skin. They'll then insert the naltrexone implant into the pocket they've created under the skin and close the incision using stitches or adhesive strips. They will also apply a sterile dressing to the area to protect it as it heals.

The procedure usually takes about 20 minutes or less you can go home the same day.

Side Effects of Naltrexone Implants

Naltrexone is generally safe. But like any medication, it can cause side effects. Here are some of the potential side effects of naltrexone implant:

Pain, swelling, or redness at the implant site
Infection at the implant site
Bleeding or bruising at the implant site
Itching or rash at the implant site
Nausea or vomiting, headache or dizziness
Diarrhea
Anxiety or nervousness
Fatigue or weakness
Liver problems
Allergic reactions

It's important to note that these side effects are usually mild and temporary, and most people tolerate the medication well. However, if you experience severe or persistent side effects, you should contact your healthcare provider immediately.

If you have any medical conditions or take other medications, inform your healthcare provider before starting a naltrexone implant to ensure it's safe and effective for you.

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Starting Naltrexone Treatment

Before starting Naltrexone, you must undergo an assessment to ensure you're suited for treatment. A good candidate for Naltrexone treatment would typically meet the following criteria:

Remain at risk of relapse without treatment
Have completed a detoxification program and have been opioid- or alcohol-free for at least 7-10 days
Used low doses of opioids or for a short time
Have a solid motivation to stop using opioids or alcohol
Are currently using other forms of evidence-based medications but would like to switch to Naltrexone
Have previously relapsed with other MAT treatments, like buprenorphine-naloxone or methadone

Naltrexone implants are a cutting-edge treatment for addiction to opioids, heroin, and alcohol. But the FDA has not approved the implantable version of Naltrexone for use in America. The treatment is only available in Europe and Australia. Still, many centers offer other forms of Naltrexone, which also offer long-term maintenance.

For more details about Naltrexone, reach out to More Than Rehab today.

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Do Harm Reduction Efforts Actually Lower Addiction Rates?

In recent years, there has been a growing movement in the United States to adopt harm reduction strategies when it comes to drug addiction and overdose. Harm reduction is a public health approach that focuses on reducing the negative consequences of risky behaviors rather than on eliminating the behaviors themselves. Proponents of harm reduction argue that this approach is more realistic and effective than traditional approaches that focus on abstinence.

There is some evidence to support this claim. For example, a study of needle exchange programs in the United States found that these programs were associated with lower rates of HIV/HSV infections among injection drug users. Another study by SAMHSA notes that these programs save lives by being accessible and available in a way that underlines the need for compassion and humility toward people who use drugs.

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SAMHSA adds that harm reduction programs provide access to treatment, social services, and health care. They reduce chronic diseases such as HIV/HCV, overdose deaths, and acute life-threatening infections related to unsterile drug injection.

However, it is important to note that harm reduction efforts alone are not enough to address the underlying causes of addiction; they must be part of a comprehensive strategy that includes prevention, treatment, and recovery services. Nevertheless, harm reduction programs can play an important role in saving lives and reducing the harms associated with drug use.

What is Harm Reduction, and what are its Goals?

Harm reduction is a public health approach that seeks to minimize the harms associated with harmful behaviors. It is rooted in the belief that people have the right to make their own choices about their health and well-being and that everyone has the potential to reduce the harms they experience.

Harm reduction approaches provide a non-judgmental way to connect people with services and support. By focusing on reducing harm rather than on eliminating risk, harm reduction provides a more realistic and achievable goal for many people. As a result, it has the potential to improve individual and population health outcomes. The principles of harm reduction include:

· Respect for autonomy: People should be free to choose their health and well-being without coercion or judgment.

· Meeting people where they are: Services and support should be tailored to meet the needs of each individual, based on their unique circumstances.

· Harm reduction is not abstinence: The focus is on reducing harm, not eliminating all risk.

· Harm reduction is pragmatic: It recognizes that people will engage in risky behaviors and seeks to minimize the associated harm.

· Harm reduction is evidence-based: It is based on the best available evidence rather than ideology. Harm Reduction Programs and Services A variety of harm reduction strategies can be employed to achieve the goals.

Some common harm reduction strategies include:

Needle Exchange Programs

Needle exchange programs provide clean needles and syringes to people who inject drugs to reduce the risk of HIV, AIDS and other blood-borne diseases. These programs also provide other services such as counseling, referrals to addiction treatment and recovery services, and access to naloxone, a medication that can reverse an opioid overdose.

Nearly three-decade of research has shown that these programs were associated with lower rates of HIV, hepatitis, and other infections. The research also found that SSP users are 5x more likely to enter drug treatment and about 3x more likely to stop using drugs than those who don't use the programs.

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The Use of Federal Funding to Purchase Fentanyl Strips

Fentanyl strips test for the presence of fentanyl in drugs. Fentanyl is a powerful synthetic opioid that is up to 100 times more potent than heroin. It is often mixed with other drugs without the user's knowledge, which can lead to accidental overdoses.

Drug checking with fentanyl strips can reduce this. The US government has funded states and localities to purchase fentanyl strips as a harm reduction measure. The strips can be used to test drugs for the presence of fentanyl, which can help users make informed decisions about whether or not to use them.

Providing Safer Consumption Spaces

Safer consumption spaces are places where people can consume drugs under the supervision of trained staff. These spaces can provide various services, including access to clean needles and syringes, naloxone, counseling, and referrals to addiction treatment and recovery services. They also educate individuals on how to reduce substance use and drug-related harm and curb the spread of infectious diseases. Today, over 66 safe consumption spaces are operating with the approval of law enforcement worldwide, including in Europe, Canada, and Australia.

Increasing Access to Opioid Overdose Reversal Treatments

Opioid overdose reversal treatments, such as Narcan® or naloxone, can save lives by reversing the effects of an opioid overdose. Naloxone is a medication that can be administered by injection or nasal spray, and it is available without a prescription in many states. Many states have implemented standing orders programs, which allow health care providers to prescribe naloxone to people who may be at risk of overdosing. The drugs can also be issued to friends and family members of people who use opioids.

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Know Your Source

Know Your Source is a harm reduction program in Vancouver, Canada, that provides information about the purity and potency of drugs to users. The program also encourages users to inject slowly, use in the presence of a sober friend and be aware of the early signs of overdose and how to use naloxone.

Medication Assisted Treatment

Medication-assisted treatment (MAT) is a harm reduction approach that combines behavioral therapy with medications to treat substance use disorders. MAT is used to treat opioid addiction and effectively reduces the risk of overdose and death.

These are just a few examples of harm reduction programs and services that can be employed to reduce the risks associated with substance use. Many other harm reduction strategies can be used, and the best approach will vary depending on the community's needs. If you or someone you know is struggling with substance use, resources are available to help. Treatment and recovery services can provide the support you need to overcome addiction and build a healthier, happier life.